Dennehy, M.D., Charles Leach, M.D., Mobeen Rathore, M.D., Nazha Abughali, M.D., Peter Wright, M.D., Lisa M. Frenkel, M.D., Rebecca C. Brady, M.D., Russell Van Dyke, M.D., Leonard B. Weiner, M.D., Judith Guzman-Cottrill, D.O., Carol A. McCarthy, M.D., Griffin Jill, R.N., Penelope Jester, R.N., M.P.H., Misty Parker, M.D., Fred D. Lakeman, Ph.D., Huichien Kuo, M.S., Choo Hyung Lee, M.S., and Gretchen A. Cloud, M.S. For the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Research Group: Oral Acyclovir Suppression and Neurodevelopment after Neonatal Herpes The outcomes of neonatal herpes simplex virus disease are dependent on the extent of the condition.1 Approximately 30 percent of infants with disseminated disease die, but only 20 percent of survivors possess neurologic sequelae.2 On the other hand, only 6 percent of babies with central nervous system disease die, but approximately 70 percent have long term neurologic impairment.2 Skin, eye, and mouth area disease is not connected with loss of life, and neurologic impairment is rare with this manifestation of neonatal herpes.3 HSV establishes latency in sensory ganglia, with periodic reactivation and recurrence of localized disease.4,5 Whether the virus subclinically reactivates in the mind after neonatal HSV disease is not known.Patients had received care from one of more than 1,200 providers at among 90 practices over the national country. About 70 % had been treated at services that had both doctors and so-known as advanced practice providers on staff. The others had only physicians. The study authors initial compared the quality of heart care supplied by doctors versus their nondoctor counterparts in facilities staffed with both. Another analysis compared heart care provided by doctor-only facilities versus treatment from nurse practitioners/doctor assistants in facilities with both. Only about 12 % of either doctors or nurse practitioners/physician assistants were found to meet almost all heart care standards with regard to basic screening and treatment protocols.