Found in the liver, CYP1A2 is in charge of processing several chemicals ingested when we eat or drink according to Vidya Perera a final year PhD student in the Faculty of Pharmacy who’s studying the mechanisms of the enzyme. But his work in addition has found an increased level of activity of CYP1A2 in females who both smoke and drink caffeine. The effects of huge amounts of caffeine in the long run remain being investigated nonetheless it has been associated with cardiac issues in older age, while improved CYP1A2 activity has been associated with several cancers.This contract will allow us to accelerate the development of 10150 as a medical countermeasure, and it’ll also, significantly, allow us to increase its development for use in oncology indications, where it would be used in combination with radiation therapy. We believe that the dual-use, broad-spectrum characteristics of AEOL 10150 make it an extremely exciting and unique substance with excellent potential. AEOL 10150 is currently also becoming studied by the National Institutes of Health’s National Institute of Allergy and Infectious Illnesses Radiation/Nuclear Medical Countermeasures development program as a countermeasure for radiation contact with the gastrointestinal system and by NIH CounterACT as countermeasure against chlorine gas and sulfur mustard gas exposure.